Mónica Leticia Martínez Pacheco

Systems Biology and Synthetic Biology Laboratory Postdoctoral Fellow


Academic history

Mónica Martínez Pacheco coursed her undergraduate studies in Biology at Faculty of Sciences of the National Autonomous University of Mexico (UNAM), Mexico. She completed her postgraduate studies in the Biomedical Sciences PhD program (PDCB), at the Institute of Biomedical Research (IIBm) from the same University, and achieved them in 2015 through her thesis defense, which was focused on the study of the global expression profile of mRNAs and miRNAs during the carcinogenesis process associated to a metal mixture exposure, where she obtained with Honors the degree of Dr. of Science.
In that same year, she worked as a Research Assistant in the Department of Genomic Medicine and Environmental Toxicology at IIBm, UNAM.
In 2016, she carried out a postdoctoral stay in Functional Genomics in the Laboratory of Dr. Araxi Urrutia Odabachian, in the Department of Biology and Biochemistry of the University of Bath, United Kingdom. During her stay, she analyzed transcriptome data sets obtained through RNA sequencing (RNA-seq) experiments with the aim of elucidating a common expression pattern for different types of cancer in order to explain the general etiology of the disease.
Later, in 2018, she lectured the course “mRNAs and miRNAs in cancer” at the Biomedical Sciences PhD Program (PDCB) from UNAM, which was addressed to students from the postgraduate Programs in Biomedical, Biochemical, and Biological Sciences of such University.
Currently, she is making a postdoctoral stay, funded by the National Council of Science and Technology (CONACyT), Mexico, with Dr. Diego Cortez Quezada at the Laboratory of Systems Biology and Synthetic Biology of the Center for Genomic Sciences (CCG) of UNAM and the research she is working on is entitled “Genomic causes of imbalance of sex ratio in adult tetrapods”.



Selected publications

Martínez-Pacheco M., Hidalgo-Miranda A., Romero-Cordoba S., Valverde M. and Rojas E. MRNA and miRNA expression patterns associated to pathways linked to metal mixture health effects. Gene 533:508-514 (2014).

Tovar-Sánchez E., Mussali-Galante P., Martínez-Pacheco M., Ortiz-Hernández M., Sánchez-Salinas E. and Olvera-Velona A. Relationship between genotoxic damage and arsenic blood concentrations in individuals residing in an arsenic contaminated area in Morelos, Mexico. Revista Internacional de Contaminación Ambiental 32:101-117 (2016).

Telephone: (777) 3291686
Email: monicamp@ccg.unam.mx


2020Martínez-Pacheco, M, Tenorio, M, Almonte, L, Fajardo, V, Godínez, A, Fernández, D, Cornejo-Páramo, P, Díaz-Barba, K, Halbert, J, Liechti, A, Székely, T, Urrutia, A, Cortez, D. (2020). "Expression Evolution of Ancestral XY Gametologs across All Major Groups of Placental Mammals.". Genome Biology And Evolution. 12(11):2015-2028. [doi:10.1093/gbe/evaa173]32790864
2020Cornejo-Páramo, P, Dissanayake, D, Lira-Noriega, A, Martínez-Pacheco, M, Acosta, A, Ramírez-Suástegui, C, Méndez-de-la-Cruz, F, Székely, T, Urrutia, A, Georges, A, Cortez, D. (2020). "Viviparous Reptile Regarded to Have Temperature-Dependent Sex Determination Has Old XY Chromosomes.". Genome Biology And Evolution. 12(6):924-930. [doi:10.1093/gbe/evaa104]32433751
2020Rojas, E, Martinez-Pacheco, M, Rodriguez-Sastre, M, Ramos-Espinosa, P, Valverde, M. (2020). "Post-transcriptional regulation of Rad51c by miR-222 contributes cellular transformation.". Plos One. 15(1):e0221681-. [doi:10.1371/journal.pone.0221681]31923208
2019Acosta, A, Martínez-Pacheco, M, Díaz-Barba, K, Porras, N, Gutiérrez-Mariscal, M, Cortez, D. (2019). "Deciphering Ancestral Sex Chromosome Turnovers Based on Analysis of Male Mutation Bias.". Genome Biology And Evolution. 11(11):3054-3067. [doi:10.1093/gbe/evz221]31605487