Biología de Sistemas y Biología Sintética

Somos un programa multidisciplinario conformado por 8 investigadores que utilizan cotidianamente un gran número de enfoques y modelos de estudio. Estamos interesados en combinar la biología de sistemas y sintética usando modelamiento a escala genómica para el diseño de fenotipos bacterianos de interés biotecnológico (Dr. José Utrilla). Además, también estamos interesados en utilizar un enfoque teórico-experimental para estudiar los mecanismos genéticos y metabólicos que permiten a poblaciones de bacterias implementar estrategias colectivas para sobrevivir a medios ambientes hostiles e impredecibles, por ejemplo a sustancias antimicrobianas (Dr. Rafael Peña). En este sentido, también nos interesa estudiar el efecto de la estructura espacial en la dinámica temporal de la evolución de la resistencia a distintas combinaciones de antibióticos (Dra. Ayari Fuentes). Asimismo, construimos modelos evolutivos para analizar regiones específicas de los genomas de los organismos, como por ejemplo los cromosomas sexuales, que son uno de los elementos más dinámicos de los genomas de los vertebrados (Dr. Diego Cortez). Utilizando como modelo de experimentación la fijación biológica de nitrógeno, estudiamos la regulación de la expresión de genes en respuesta a diferentes estímulos del medio ambiente y los mecanismos que gobiernan esta respuesta (Dra. María de Lourdes Girard). También estudiamos la transducción de señales y la regulación genética en el género Vibrio (Dr. David Zamorano). Por otro lado analizamos la metagenómica de la piel de los anfibios y su interacción con hongos patógenos (Dra. Eria Rebollar). Finalmente, estudiamos los principios a nivel de sistemas gobernando la organización y evolución de la circuitería biológica a escala global (Dr. Julio Freyre).

Académicos del Grupo

NombrePuestoCategoríaCorreoTeléfono
María de Lourdes Girard CuesyInvestigadorInv. Tit. B T.C. Definitivogirard@ccg.unam.mx(777) 3291686
Diego Cortez QuezadaInvestigadorInv. Tit. A T.C. Interinodcortez@ccg.unam.mx(777) 3291686
Ayari Fuentes HernándezInvestigadorInv. Tit. A T.C. Interinoayarifh@ccg.unam.mx(777) 3291686
Marisa Rodríguez PadillaTécnico AcadémicoTec. Acad. Asoc. B T.C. Obra Det.marrodri@ccg.unam.mx(777) 3291686
José Utrilla CarreriInvestigadorInv. Tit. A T.C. Interinoutrilla@ccg.unam.mx(777) 3291686
Eria Rebollar CaudilloInvestigadorInv. Asoc. C T.C. Interinorebollar@ccg.unam.mx(555) 622 7777, Red-UNAM 38489
David Salvador Zamorano SánchezInvestigadorInv. Asoc. C T.C. Interinozamorano@ccg.unam.mx(777) 329 1777
María de la Paz Elizabeth Salas OcampoTécnico AcadémicoTec. Acad. Asoc. C T.C. Obra Det.pesalas@ccg.unam.mx(777) 3291686
Rafael Peña MillerInvestigadorInv. Tit. A T.C. Interinorpm@ccg.unam.mx(777) 3291686
Julio Augusto Freyre GonzálezInvestigadorInv. Tit. A T.C. Interinojfreyre@ccg.unam.mx(777) 3133881
Fernando Santos EscobarPosdoctoralDGAPAfesantos@ccg.unam.x(777) 3291686
José Arcadio Farías RicoInvestigadorInv. Asoc. C T.C. Interinojafarias@ccg.unam.mx(777) 3291686
María Magdalena Banda HernándezPosdoctoralDGAPAbandahmm@ccg.unam.mx(777) 3291686
Mishael Sánchez PérezTécnico por honorariosOtromishael@ccg.unam.mx(777) 3132063
Claudia Ivonne Hernández ArmentaPosdoctoralDGAPAchernand@ccg.unam.mx(777) 3291686
María Delia Basanta PosdoctoralCONACYTdelibasanta@gmail.com(777) 3291686

Publicaciones del Grupo

AñoPublicaciónPMID
2020Rodriguez, S, Correa-Galeote, D, Sanchez-Perez, M, Ramirez, M, Isidra-Arellano, M, Reyero-Saavedra, M, Zamorano-Sanchez, D, Hernandez, G, Valdes-Lopez, O, Girard, L. (2020). "A Novel OmpR-Type Response Regulator Controls Multiple Stages of the Rhizobium etli – Phaseolus vulgaris N2-Fixing Symbiosis". Frontiers in Microbiology. 11():615775-. [doi:10.3389/fmicb.2020.615775]33384681
2020Rebollar, E, Martínez-Ugalde, E, Orta, A. (2020). "The Amphibian Skin Microbiome and Its Protective Role Against Chytridiomycosis". Herpetologica. 76(2):167-177. [doi:10.1655/0018-0831-76.2.167]
2020Escorcia-Rodríguez, J, Tauch, A, Freyre-González, J. (2020). "Abasy Atlas v2.2: The most comprehensive and up-to-date inventory of meta-curated, historical, bacterial regulatory networks, their completeness and system-level characterization.". Computational and Structural Biotechnology Journal. 18():1228-1237. [doi:10.1016/j.csbj.2020.05.015]32542109
2020Ide, A, Hernández, V, Medina-Aparicio, L, Carcamo-Noriega, E, Girard, L, Hernández-Lucas, I, Dunn, M. (2020). "Genetic regulation, biochemical properties and physiological importance of arginase from Sinorhizobium meliloti". MICROBIOLOGY-SGM. 166(5):484-497. [doi:10.1099/mic.0.000909]32216867
2020Rojas, E, Martinez-Pacheco, M, Rodriguez-Sastre, M, Ramos-Espinosa, P, Valverde, M. (2020). "Post-transcriptional regulation of Rad51c by miR-222 contributes cellular transformation.". Plos One. 15(1):e0221681-. [doi:10.1371/journal.pone.0221681]31923208
2020Wu, D, Zamorano-Sánchez, D, Pagliai, F, Park, J, Floyd, K, Lee, C, Kitts, G, Rose, C, Bilotta, E, Wong, G, Yildiz, F. (2020). "Reciprocal c-di-GMP signaling: Incomplete flagellum biogenesis triggers c-di-GMP signaling pathways that promote biofilm formation.". Plos Genetics. 16(3):e1008703-. [doi:10.1371/journal.pgen.1008703]32176702
2020Kim, J, Darlington, A, Salvador, M, Utrilla, J, Jiménez, J. (2020). "Trade-offs between gene expression, growth and phenotypic diversity in microbial populations". CURRENT OPINION IN BIOTECHNOLOGY. 62():29-37. [doi:10.1016/j.copbio.2019.08.004]31580950
2020Ferruz N, Lobos F, Lemm D, Toledo-Patino S, Farías-Rico JA, Schmidt S, Höcker B. (2020). "Identification and Analysis of Natural Building Blocks for Evolution-Guided Fragment-Based Protein Design.". Journal Of Molecular Biology. 432(13):3898-3914. [doi:10.1016/j.jmb.2020.04.013]32330481
2020Sanjuan, J, Delgado, M, Girard, L. (2020). "Editorial: Microbial Control of the Nitrogen Cycle.". Frontiers in Microbiology. 11():950-. [doi:10.3389/fmicb.2020.00950]32477318
2020Martínez-Ortiz, I, Ahumada-Manuel, C, Hsueh, B, Guzmán, J, Moreno, S, Cocotl-Yañez, M, Waters, C, Zamorano-Sánchez, D, Espín, G, Núñeza, C. (2020). "Cyclic di-GMP-Mediated Regulation of Extracellular Mannuronan C-5 Epimerases Is Essential for Cyst Formation in Azotobacter Vinelandii.". Journal Of Bacteriology. 202(24):e00135-20-. [doi:10.1128/JB.00135-20]32989089
2020Cornejo-Páramo, P, Dissanayake, D, Lira-Noriega, A, Martínez-Pacheco, M, Acosta, A, Ramírez-Suástegui, C, Méndez-de-la-Cruz, F, Székely, T, Urrutia, A, Georges, A, Cortez, D. (2020). "Viviparous Reptile Regarded to Have Temperature-Dependent Sex Determination Has Old XY Chromosomes.". Genome Biology And Evolution. 12(6):924-930. [doi:10.1093/gbe/evaa104]32433751
2020Rodríguez-Beltrán, J, Sørum, V, Toll-Riera, M, de la Vega, C, Peña-Miller, R, Millán, Á. (2020). "Genetic dominance governs the evolution and spread of mobile genetic elements in bacteria.". PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 117(27):15755-15762. [doi:10.1073/pnas.2001240117]32571917
2020Cornejo-Páramo, P, Lira-Noriega, A, Ramírez-Suástegui, C, Méndez-De-La-Cruz, F, Székely, T, Urrutia, A, Cortez, D. (2020). "Sex determination systems in reptiles are related to ambient temperature but not to the level of climatic fluctuation.". Bmc Evolutionary Biology. 20(1):103-. [doi:10.1186/s12862-020-01671-y]32807071
2020Lastiri-Pancardo, G, Mercado-Hernández, J, Kim, J, Jiménez, J, Utrilla, J. (2020). "A quantitative method for proteome reallocation using minimal regulatory interventions.". NATURE CHEMICAL BIOLOGY. 16(9):1026-1033. [doi:10.1038/s41589-020-0593-y]32661378
2020de la Cruz, M, Ramírez, E, Sigala, J, Utrilla, J, Lara, A. (2020). "Plasmid DNA Production in Proteome-Reduced Escherichia coli .". Microorganisms. 8(9):1-8. [doi:10.3390/microorganisms8091444]32967123
2020Moreno-Avitia, F, Utrilla, J, Bolivar, F, Nogales, J, Escalante, A. (2020). "Metabolic reconstruction ofPseudomonas chlororaphisATCC 9446 to understand its metabolic potential as a phenazine-1-carboxamide-producing strain". Applied Microbiology And Biotechnology. 104(23):10119-10132. [doi:10.1007/s00253-020-10913-4]32984920
2020Martínez-Pacheco, M, Tenorio, M, Almonte, L, Fajardo, V, Godínez, A, Fernández, D, Cornejo-Páramo, P, Díaz-Barba, K, Halbert, J, Liechti, A, Székely, T, Urrutia, A, Cortez, D. (2020). "Expression Evolution of Ancestral XY Gametologs across All Major Groups of Placental Mammals.". Genome Biology And Evolution. 12(11):2015-2028. [doi:10.1093/gbe/evaa173]32790864
2020Gutiérrez-Guerrero, Y, Ibarra-Laclette, E, Martínez Del Río, C, Barrera-Redondo, J, Rebollar, E, Ortega, J, León-Paniagua, L, Urrutia, A, Aguirre-Planter, E, Eguiarte, L. (2020). "Genomic consequences of dietary diversification and parallel evolution due to nectarivory in leaf-nosed bats.". GigaScience. 9(6):giaa059-. [doi:10.1093/gigascience/giaa059]32510151
2019Santos-Zavaleta, A, Pérez-Rueda, E, Sánchez-Pérez, M, Velázquez-Ramírez, D, Collado-Vides, J. (2019). "Tracing the phylogenetic history of the Crl regulon through the Bacteria and Archaea genomes.". Bmc Genomics. 20(1):299-. [doi:10.1186/s12864-019-5619-z]30991941
2019Bañuelos-Vazquez, L, Torres Tejerizo, G, Cervantes-De La Luz, L, Girard, L, Romero, D, Brom, S. (2019). "Conjugative transfer between Rhizobium etli endosymbionts inside the root nodule". Environmental Microbiology. 21(9):3430-3441. [doi:10.1111/1462-2920.14645]31037804
2019Santos-Zavaleta, A, Salgado, H, Gama-Castro, S, Sánchez-Pérez, M, Gómez-Romero, L, Ledezma-Tejeida, D, García-Sotelo, J, Alquicira-Hernández, K, Muñiz-Rascado, L, Peña-Loredo, P, Ishida-Gutiérrez, C, Velázquez-Ramírez, D, Del Moral-Chávez, V, Bonavides-Martínez, C, Méndez-Cruz, C, Galagan, J, Collado-Vides, J. (2019). "RegulonDB v 10.5: tackling challenges to unify classic and high throughput knowledge of gene regulation in E. coli K-12". Nucleic Acids Research. 47(D1):212-220. [doi:10.1093/nar/gky1077]30395280
2019Delia Basanta, M, Rebollar, E, Parra-Olea, G. (2019). "Potential risk of Batrachochytrium salamandrivorans in Mexico". Plos One. 14(2):e0211960-. [doi:10.1371/journal.pone.0211960]30753218
2019Astudillo-Melgar, F, Ochoa-Leyva, A, Utrilla, J, Huerta-Beristain, G. (2019). "Bacterial Diversity and Population Dynamics During the Fermentation of Palm Wine From Guerrero Mexico.". Frontiers in Microbiology. 10():531-. [doi:10.3389/fmicb.2019.00531]30967846
2019Hernández-Rodríguez, D, Vásquez-Aguilar, A, Serio-Silva, J, Rebollar, E, Azaola-Espinosa, A. (2019). "Molecular detection of Bifidobacterium spp. in faeces of black howler monkeys (Alouatta pigra)". JOURNAL OF MEDICAL PRIMATOLOGY. 48(2):99-105. [doi:10.1111/jmp.12395]30520095
2019Kueneman, J, Bletz, M, McKenzie, V, Becker, C, Joseph, M, Abarca, J, Archer, H, Arellano, A, Bataille, A, Becker, M, Belden, L, Crottini, A, Geffers, R, Haddad, C, Harris, R, Holden, W, Hughey, M, Jarek, M, Kearns, P, Kerby, J, Kielgast, J, Kurabayashi, A, Longo, A, Loudon, A, Medina, D, Nuñez, J, Perl, R, Pinto-Tomás, A, Rabemananjara, F, Rebollar, E, Rodríguez, A, Rollins-Smith, L, Stevenson, R, Tebbe, C, Vargas Asensio, G, Waldman, B, Walke, J, Whitfield, S, Zamudio, K, Zúñiga Chaves, I, Woodhams, D, Vences, M. (2019). "Community richness of amphibian skin bacteria correlates with bioclimate at the global scale". Nature Ecology & Evolution. 3(3):381-389. [doi:10.1038/s41559-019-0798-1]30778181
2019Alaide Rebollar, E, Harris, R. (2019). "Editorial: Ecology of Amphibian-Microbial Symbioses.". Frontiers in Microbiology. 10():766-. [doi:10.3389/fmicb.2019.00766]31057502
2019Keiser, C, Wantman, T, Rebollar, E, Harris, R. (2019). "Tadpole body size and behaviour alter the social acquisition of a defensive bacterial symbiont". Royal Society open science. 6(9):191080-191080. [doi:10.1098/rsos.191080]31598324
2019Acosta, A, Martínez-Pacheco, M, Díaz-Barba, K, Porras, N, Gutiérrez-Mariscal, M, Cortez, D. (2019). "Deciphering Ancestral Sex Chromosome Turnovers Based on Analysis of Male Mutation Bias.". Genome Biology And Evolution. 11(11):3054-3067. [doi:10.1093/gbe/evz221]31605487
2019Gabriel Suárez-Varón, Orlando Suárez-Rodríguez, Gisela Granados-González, Maricela Villagrán-Santa Cruz, Kevin M. Gribbins, Diego Cortez-Quezada, Oswaldo Hernández-Gallegos. (2019). "Relative clutch mass of Basiliscus vittatus Wiegmann, 1828 (Squamata, Corytophanidae): female morphological constraints". Herpetozoa. 32(3):211-219. [doi:10.3897/herpetozoa.32.e35910]
2019Hidalgo-Garcia, A, Torres, M, Sales, A, Bedmar, E, Girard, L, Delgado, M. (2019). "Rhizobium etli Produces Nitrous Oxide by Coupling the Assimilatory and Denitrification Pathways". Frontiers in Microbiology. 10():980-980. [doi:10.3389/fmicb.2019.00980]31134023
2019Acosta, A, Suárez-Varón, G, Rodríguez-Miranda, L, Lira-Noriega, A, Aguilar-Gómez, D, Gutiérrez-Mariscal, M, Hernández-Gallegos, O, Méndez-de-la-Cruz, F, Cortez, D. (2019). "Corytophanids Replaced the Pleurodont XY System with a New Pair of XY Chromosomes.". Genome Biology And Evolution. 11(9):2666-2677. [doi:10.1093/gbe/evz196]31557287
2019Estrada, A, Hughey, M, Medina, D, Rebollar, E, Walke, J, Harris, R, Belden, L. (2019). "Skin bacterial communities of neotropical treefrogs vary with local environmental conditions at the time of sampling.". Peerj. 7():e7044-. [doi:10.7717/peerj.7044]31275740
2019Rebollar, E, Bridges, T, Hughey, M, Medina, D, Belden, L, Harris, R. (2019). "Integrating the role of antifungal bacteria into skin symbiotic communities of three Neotropical frog species". ISME JOURNAL. 13(7):1763-1775. [doi:10.1038/s41396-019-0388-x]30867545
2018Chiozzotto, R, Ramirez, M, Talbi, C, Cominelli, E, Girard, L, Sparvoli, F, Hernandez, G. (2018). "Characterization of the symbiotic nitrogen-fixing common bean Low Phytic Acid (lpa1) mutant response to water stress". Genes. 9(2):99-. [doi:10.3390/genes9020099]29462877
2018Rodriguez-Beltran, J, Hernandez-Beltran, J, Delafuente, J, Escudero, J, Fuentes-Hernandez, A, MacLean, R, Peña-Miller, R, San Millan, A. (2018). "Multicopy plasmids allow bacteria to escape from fitness trade-offs during evolutionary innovation". Nature Ecology & Evolution. 2(5):873-881. [doi:10.1038/s41559-018-0529-z]29632354
2018Latif, H, Federowicz, S, Ebrahim, A, Tarasova, J, Szubin, R, Utrilla, J, Zengler, K, Palsson, B. (2018). "ChIP-exo interrogation of Crp, DNA, and RNAP holoenzyme interactions". Plos One. 13(5):e0197272-. [doi:10.1371/journal.pone.0197272]29771928
2018Aguilar A, Mora Y, Dávalos A, Girard L, Mora J, Peralta H. (2018). "Analysis of genome sequence and symbiotic ability of rhizobial strains isolated from seeds of common bean (Phaseolus vulgaris).". Bmc Genomics. 19(1):645-645. [doi:10.1186/s12864-018-5023-0]30165827
2018Isidra-Arellano, M, Reyero-Saavedra, M, Sánchez-Correa, M, Pingault, L, Sen, S, Joshi, T, Girard, L, Castro-Guerrero, N, Mendoza-Cozatl, D, Libault, M, Valdés-López, O. (2018). "Phosphate deficiency negatively affects early steps of the symbiosis between common bean and Rhizobia". Genes. 9(10):498-. [doi:10.3390/genes9100498]30326664
2017Vargas-Lagunas, C, Mora, Y, Diaz, R, Martinez-Batallar, G, Girard, L, Encarnacion, S, Peralta, H, Mora, J. (2017). "Overproduction of Sinorhizobium meliloti argC (N-acetyl-gamma-glutamyl phosphate reductase) promotes growth delay and inefficient nodules". Fems Microbiology Letters. 364(23):fnx233-. [doi:10.1093/femsle/fnx233]29121239
2017Moreno-Avitia, F, Lozano, L, Utrilla, J, Bolívar, F, Escalante, A. (2017). "Draft genome sequence of pseudomonas chlororaphis ATCC 9446, a nonpathogenic bacterium with bioremediation and industrial potential". Microbiology Resource Announcements. 5(23):e00474-17-. [doi:10.1128/genomeA.00474-17]28596401
2017Utrilla, J. (2017). "Evolutionary Engineering of Microorganisms to Overcome Toxicity During Lignocellulose Hydrolysates Utilization". Engineering of Microorganisms for the Production of Chemicals and Biofuels from Renewable Resources. ():181-200. [doi:https://doi.org/10.1007/978-3-319-51729-2_7]
2017Steffani-Vallejo, J, Zuñiga, C, Cruz-Morales, P, Lozano, L, Morales, M, Licona-Cassani, C, Revah, S, Utrilla, J. (2017). "Draft genome sequence of Sphingobacterium sp. CZ-UAM, isolated from a methanotrophic consortium". Microbiology Resource Announcements. 5(33):e00792-17-. [doi:10.1128/genomeA.00792-17]28818899
2016Utrilla, J, Vargas-Tah, A, Trujillo-Martinez, B, Gosset, G, Martinez, A. (2016). "Production of D-lactate from sugarcane bagasse and corn stover hydrolysates using metabolic engineered Escherichia coli strains". BIORESOURCE TECHNOLOGY. 220():208-214. [doi:10.1016/j.biortech.2016.08.067]27573474
2016Aguilar A, Peralta H, Mora Y, Díaz R, Vargas-Lagunas C, Girard L, Mora J. (2016). "Genomic comparison of Agrobacterium Pusense strains isolated from bean nodules". Frontiers in Microbiology. 7(OCT):1720-1720. [doi:10.3389/fmicb.2016.01720]27833604
2016Peralta H, Aguilar A, Díaz R, Mora Y, Martínez-Batallar G, Salazar E, Vargas-Lagunas C, Martínez E, Encarnación S, Girard L, Mora J. (2016). "Genomic studies of nitrogen-fixing rhizobial strains from Phaseolus vulgaris seeds and nodules". Bmc Genomics. 17(1):1-1. [doi:10.1186/s12864-016-3053-z]27601031
2016Reyes-Gonzalez, A, Talbi, C, Rodriguez, S, Rivera, P, Zamorano-Sanchez, D, Girard, L. (2016). "Expanding the regulatory network that controls nitrogen fixation in Sinorhizobium meliloti: elucidating the role of the two-component system hFixL-FxkR". MICROBIOLOGY-SGM. 162(6):979-988. [doi:10.1099/mic.0.000284]27010660
2016Utrilla, J, O'Brien, E, Chen, K, McCloskey, D, Cheung, J, Wang, H, Armenta-Medina, D, Feist, A, Palsson, B. (2016). "Global Rebalancing of Cellular Resources by Pleiotropic Point Mutations Illustrates a Multi-scale Mechanism of Adaptive Evolution". Cell systems. 2(4):260-271. [doi:10.1016/j.cels.2016.04.003]27135538
2015Zamorano-Sanchez, D, Girard, L. (2015). "Fnr-Like Proteins in Rhizobia: Past and Future". Biological Nitrogen Fixation, Vols 1 And 2. ():155-165.
2015Hernandez, V, Girard, L, Hernandez-Lucas, I, Vazquez, A, Ortiz-Ortiz, C, Diaz, R, Dunn, M. (2015). "Genetic and biochemical characterization of arginine biosynthesis in Sinorhizobium meliloti 1021". MICROBIOLOGY-SGM. 161(8):1671-1682. [doi:10.1099/mic.0.000122]26271664
2015Nova-Franco B, Íñiguez LP, Valdés-López O, Alvarado-Affantranger X, Leija A, Fuentes SI, Ramírez M, Paul S, Reyes JL, Girard L, Hernández G. (2015). "The Micro-RNA172c-APETALA2-1 Node as a Key Regulator of the Common Bean-Rhizobium etli Nitrogen Fixation Symbiosis". Plant Physiology. 168(1):273-502. [doi:10.1104/pp.114.255547]25739700
2015Girard Cuesy, M, Zamorano Sánchez, D. (2015). "Fnr - like proteins in Rhizobia: past and future". Biological Nitrogen Fixation. 1():155-166. [doi:10.1002/9781119053095]
2014Mora, Y, Diaz, R, Vargas-Lagunas, C, Peralta, H, Guerrero, G, Aguilar, A, Encarnacion, S, Girard, L, Mora, J. (2014). "Nitrogen-fixing rhizobial strains isolated from common bean seeds: Phylogeny, physiology, and genome analysis". Applied And Environmental Microbiology. 80(18):5644-5654. [doi:10.1128/AEM.01491-14]25002426
2014Garcia-Garcia, J, Girard Cuesy, M, Hernández Delgado, G, Saavedra, E, Pardo, J, Rodríguez-Zavala, J, Encalada, R, Reyes-Prieto, A, Mendoza-Cozatl, D, Moreno-Sánchez, R. (2014). "Zn-bis-glutathionate is the best co-substrate of the monomeric phytochelatin synthase from the photosynthetic heavy metal-hyperaccumulator Euglena Gracilis". Metallomics. 6(3):604-616. [doi:10.1039/c3mt00313b]24464102
2013Ramírez Yáñez, M, Guillén, G, Fuentes Membreño, S, Iñiguez Rabago, L, Aparicio Fabre, R, Zamorano Sánchez, D, Encarnación Guevara, S, Panzeri, D, Castiglioni, B, Cremonesi, P, Strozzi, F, Stella, A, Girard Cuesy, M, Sparvoli, F, Hernández Delgado, G. (2013). "Transcript profiling of common bean nodules subjected to oxidative stress". Physiologia Plantarum. 149(3):389-407. [doi:10.1111/ppl.12040]23432573
2013Reyes González, A, Zamorano Sánchez, D, Rivera Rosas, P, Girard Cuesy, M. (2013). "hFixL-FxkR are the key regulators for fixKf-related gene expression". Mexican Journal of Scientific Research. ():-.
2013Ramírez Yáñez, M, Flores-Pacheco, G, Reyes, J, Álvarez, A, Drevon, J, Girard Cuesy, M, Hernández Delgado, G. (2013). "Two Common Bean Genotypes with Contrasting Response to Phosphorus Deficiency Show Variations in the microRNA 399-Mediated PvPHO2 Regulation within the PvPHR1 Signaling Pathway". International Journal Of Molecular Sciences. 14(4):8328-8344. [doi:10.3390/ijms14048328]23591845
2013Aparicio Fabre, R, Guillén, G, Loredo, M, Arellano García, J, Valdes López, O, Ramírez Yáñez, M, Iñiguez Rabago, L, Panzeri, D, Castiglioni, B, Cremonesi, P, Strozzi, F, Stella, A, Girard Cuesy, M, Sparvoli, F, Hernández Delgado, G. (2013). "Common bean (Phaseolus vulgaris L.) PvTIFY orchestrates global changes in transcript profile response to jasmonate and phosphorus deficiency". Bmc Plant Biology. 13():26-26. [doi:10.1186/1471-2229-13-26]23402340
2012Zamorano Sánchez, D, Reyes-González, A, Gómez Hernández, N, Rivera, P, Georgellis, D, Girard Cuesy, M. (2012). "FxkR Provides the Missing Link in the fixL-fixK Signal Transduction Cascade in Rhizobium etli CFN42". Molecular Plant-Microbe Interactions. 25(11):1506-1517. [doi:10.1094/MPMI-05-12-0136-R]22809273
2012García-García, J, Olin-Sandoval, V, Saavedra, E, Girard Cuesy, M, Hernández Delgado, G, Moreno-Sánchez, R. (2012). "Sulfate uptake in photosynthetic Euglena Gracilis. Mechanisms of regulation and contribution to cysteine homeostasis". Biochimica Et Biophysica Acta-General Subjects. 1820(10):1567-1575. [doi:10.1016/j.bbagen.2012.05.002]22609877
2012Talbi, C, Sánchez, C, Hidalgo-García, A, González, E, Arrese-Igor, C, Girard Cuesy, M, Bedmar, E, Delgado, M. (2012). "Enhanced expression of Rhizobium etli cbb(3) oxidase improves drought tolerance of common bean symbiotic nitrogen fixation". Journal Of Experimental Botany. 63(14):5035-5043. [doi:10.1093/jxb/ers101]22511804
2011Díaz Mendez, R, Vargas Lagunas, M, Villalobos López, M, Peralta Díaz, H, Pérez-Tejada Domínguez, Y, Encarnación Guevara, S, Girard Cuesy, M, Mora Celis, J. (2011). "argC orthologs from Rhizobiales show diverse profiles of transcriptional efficiency and functionality in Sinorhizobium meliloti". Journal Of Bacteriology. 193(2):460-472. [doi:10.1128/JB.01010-10]21075924
2011Gómez Hernández, N, Reyes González, A, Sanchez, C, Pérez-Tejada Domínguez, Y, Delgado, M, Girard Cuesy, M. (2011). "Regulation and Symbiotic Role of nirK and norC Expression in Rhizobium etli". Molecular Plant-Microbe Interactions. 24(2):233-245. [doi:10.1094/MPMI-07-10-0173]21043576
2011Cervantes de la Luz, L, Bustos Arcos, V, Girard Cuesy, M, Santamaria Gutiérrez, R, Dávila Ramos, J, Vinuesa Fleischmann, P, Romero Camarena, D, Brom Klanner, S. (2011). "The conjugative plasmid of a bean-nodulating Sinorhizobium fredii strain is assembled from sequences of two Rhizobium plasmids and the chromosome of a Sinorhizobium strain". Bmc Microbiology. 11(1):1-11. [doi:10.1186/1471-2180-11-149]21702991
2010Talbi, C, Delgado, M, Girard, L, Ramirez-Trujillo, A, Caballero-Mellado, J, Bedmar, E. (2010). "Burkholderia Phymatum Strains Capable of Nodulating Phaseolus vulgaris Are Present in Moroccan Soils". Applied And Environmental Microbiology. 76(13):4587-4591. [doi:10.1128/AEM.02886-09]20472732
2010Sanchez, C, Gates, A, Meakin, G, Uchiumi, T, Girard, L, Richardson, D, Bedmar, E, Delgado, M. (2010). "Production of Nitric Oxide and Nitrosylleghemoglobin Complexes in Soybean Nodules in Response to Flooding". Molecular Plant-Microbe Interactions. 23(5):702-711. [doi:10.1094/MPMI-23-5-0702]20367476
2010Talbi, C, Sánchez, C, Girard Cuesy, M, Bedmar, E, Delgado, M. (2010). "La sobreexpresión de la oxidasa cbb3 de Rhizobium etli incrementa la tolerancia de Phaseolus vulgaris a la sequía". Avances en el metabolismo del Nitrógeno. ():223-228.
2009Onofre-Lemus, J, Hernandez-Lucas, I, Girard, L, Caballero-Mellado, J. (2009). "ACC (1-Aminocyclopropane-1-Carboxylate) Deaminase Activity, a Widespread Trait in Burkholderia Species, and Its Growth-Promoting Effect on Tomato Plants". Applied And Environmental Microbiology. 75(20):6581-6590. [doi:10.1128/AEM.01240-09]19700546
2008Valdes-Lopez, O, Arenas-Huertero, C, Ramirez, M, Girard, L, Sanchez, F, Vance, C, Reyes, J, Hernandez, G. (2008). "Essential role of MYB transcription factor: PvPHR1 and microRNA: PvmiR399 in phosphorus-deficiency signalling in common bean roots". Plant Cell And Environment. 31(12):1834-1843. [doi:10.1111/j.1365-3040.2008.01883.x]18771575
2008Vargas, M, Villalobos, M, Diaz, R, Flores, M, Contreras, S, Encarnacion, S, Mora, Y, Dunn, M, Girard, L, Mora, J. (2008). "COMPARATIVE ANALYSIS OF argC PROTEIN EXPRESSION IN Rhizobium SPECIES". Biological Nitrogen Fixation: Towards Poverty Alleviation Through Sustainable Agriculture. 42():239-240.
2007Granados Baeza, M, Gómez Hernández, N, Mora, Y, Delgado, M, Romero Camarena, D, Girard Cuesy, M. (2007). "Novel reiterated Fnr-type proteins control the production of the symbiotic terminal oxidase cbb3 in Rhizobium etli CFN42". Molecular Plant-Microbe Interactions. 20(10):1241-1249. [doi:10.1094/MPMI-20-10-1241]17918626
2007Flores López, M, Morales Reyes, L, Gonzaga Jáuregui, C, Domínguez Vidaña, R, Zepeda Mendoza, C, Yáñez Cuna, J, Gutiérrez Arcelus, M, Lemus Vergara, T, Valle García, D, Ávila Arcos, M, Blanco Melo, D, Medina Ruiz, S, Meza Sosa, K, Ayala Ortega, E, García Alonso, D, Bustos Arcos, V, González Zúñiga, V, Girard Cuesy, M, Tusie-Luna, T, Dávila Ramos, J, Palacios de la Lama, R. (2007). "Recurrent DNA inversion rearrangements in the human genome". PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 104(15):6099-6106. [doi:10.1073/pnas.0701631104]17389356
2005Vargas, M, Encarnacion, S, Girard, M, Reyes, A, Mora, Y, Mora, J. (2005). "Characterization of the alternative protection programs against oxidative-stress in free life and symbiosis from Rhizobium etli". Biological Nitrogen Fixation, Sustainable Agriculture And The Environment. 41():331-331.
2005Bueno, E, Gomez-Hernandez, N, Girard, L, Bedmar, E, Delgado, M. (2005). "Function of the Rhizobium etli CFN42 nirK gene in nitrite metabolism". BIOCHEMICAL SOCIETY TRANSACTIONS. 33(1):162-163. [doi:10.1042/BST0330162]15667294
2005Vargas Lagunas, M, Encarnación Guevara, S, Girard Cuesy, M, Reyes Pérez, A, Pérez-Tejada Domínguez, Y, Mora Celis, J. (2005). "Characterization of the alternative protection programs against oxidative-stress in free life and simbiosis from Rhizobium etli". Current Plant Science and Biotechnology. Agriculture Biological Nitrogen Fixation, Sustainable Agriculture and the Environment. 41():331-.
2004Brom Klanner, S, Girard Cuesy, M, Tun Garrido, C, García de los Santos, A, Bustos Arcos, V, González Zúñiga, V, Romero Camarena, D. (2004). "Transfer of the symbiotic plasmid of Rhizobium etli CFN42 requires cointegration with p42a, which may be mediated by site-specific recombination". Journal Of Bacteriology. 186(22):7538-7548. [doi:10.1128/JB.186.22.7538-7548.2004]15516565
2004Vargas, M, Encarnacin, S, Girard, M, Reyes, A, Mora, Y, Mora, J. (2004). "Physiological and proteome characterizations of oxidative-stress response in Rhizobium etli during free life and symbiosis with Phaseolus vulgaris.". MOLECULAR & CELLULAR PROTEOMICS. 3(10, S):160-160.
2003González Zúñiga, V, Bustos Arcos, V, Ramírez Romero, M, Medrano Soto, L, Salgado Osorio, H, Hernández González, I, Hernández Celis, J, Quintero Hernández, V, Moreno Hagelsieb, G, Girard Cuesy, M, Rodríguez Sánchez, O, Flores López, M, Cevallos Gaos, M, Collado Vides, P, Romero Camarena, D, Dávila Ramos, J. (2003). "The mosaic structure of the symbiotic plasmid of Rhizobium etli CFN42 and its relation to other symbiotic genome compartments.". Genome Biology. 4(6):R36-. [doi:10.1186/gb-2003-4-6-r36]12801410
2002Brom Klanner, S, Girard Cuesy, M, García de los Santos, A, Sanjuan-Pinilla, J, Olivares, J, Sanjuan, J. (2002). "Conservation of plasmid-encoded traits among bean-nodulating Rhizobium species". Applied And Environmental Microbiology. 68(5):2555-2561. [doi:10.1128/AEM.68.5.2555-2561.2002]11976134
2001López, O, Morera, C, Miranda-Ríos, J, Girard Cuesy, M, Romero Camarena, D, Soberón Chávez, M. (2001). "Regulation of gene expression in response to oxygen in Rhizobium etli: Role of FnrN in fixNOQP expression and in symbiotic nitrogen fixation". Journal Of Bacteriology. 183(24):6999-7006. [doi:10.1128/JB.183.24.6999-7006.2001]11717256
2000Girard Cuesy, M, Brom Klanner, S, Dávalos Rodríguez, A, López, O, Soberón Chávez, M, Romero Camarena, D. (2000). "Differential regulation of fixN-reiterated genes in Rhizobium etli by a novel fixL-fixK cascade". Molecular Plant-Microbe Interactions. 13(12):1283-1292. [doi:10.1094/MPMI.2000.13.12.1283]11106020
2000Reyes, J, Tabche, M, Morera, C, Girard Cuesy, M, Romero Camarena, D, Krol, E, Miranda, J, Soberón Chávez, M. (2000). "Expression pattern of Rhizobium etli ccmIEFH genes involved in c-type cytochrome maturation". Gene. 250(1-2):149-157. [doi:10.1016/S0378-1119(00)00176-1]10854788
1999Soberon, M, Lopez, O, Morera, C, Girard, M, Tabche, M, Miranda, J. (1999). "Enhanced nitrogen fixation in a Rhizobium etli ntrC mutant that overproduces the Bradyrhizobium japonicum symbiotic terminal oxidase cbb(3)". Applied And Environmental Microbiology. 65(5):2015-2019. 10223993
1998Flores, M, Mavingui, P, Girard, L, Perret, X, Broughton, W, Martinez-Romero, E, Davila, G, Palacios, R. (1998). "Three replicons of Rhizobium sp. strain NGR234 harbor symbiotic gene sequences". Journal Of Bacteriology. 180(22):6052-6053. [doi:10.1128/JB.180.22.6052-6053.1998]9811668
1997RamirezRomero, M, Bustos, P, Girard, L, Rodriguez, O, Cevallos, M, Davila, G. (1997). "Sequence, localization and characteristics of the replicator region of the symbiotic plasmid of Rhizobium etli". MICROBIOLOGY-SGM. 143(8):2825-2831. [doi:10.1099/00221287-143-8-2825]9274036
1996Girard, L, Valderrama, B, Palacios, R, Romero, D, Davila, G. (1996). "Transcriptional activity of the symbiotic plasmid of Rhizobium etli is affected by different environmental conditions". MICROBIOLOGY-SGM. 142(10):2847-2856. [doi:10.1099/13500872-142-10-2847]
1996Valderrama, B, Davalos, A, Girard, L, Morett, E, Mora, J. (1996). "Regulatory proteins and CIS-acting elements involved in the transcriptional control of Rhizobium etli reiterated nifH genes". Journal Of Bacteriology. 178(11):3119-3126. [doi:10.1128/jb.178.11.3119-3126.1996]8655489
1995ROMERO, D, MARTINEZSALAZAR, J, GIRARD, L, BROM, S, DAVILA, G, PALACIOS, R, FLORES, M, RODRIGUEZ, C. (1995). "Discrete amplifiable regions (amplicons) in the symbiotic plasmid of Rhizobium etli CFN42". Journal Of Bacteriology. 177(4):973-980. [doi:10.1128/jb.177.4.973-980.1995]7860608
1993Flores López, M, Brom Klanner, S, Stepkowsky, T, Girard Cuesy, M, Dávila Ramos, J, Romero Camarena, D, Palacios de la Lama, R. (1993). "Gene amplification in Rhizobium: Identification and in vivo cloning of discrete amplifiable DNA regions (amplicons) from Rhizobium leguminosarum biovar phaseoli". PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 90(11):4932-4936. [doi:10.1073/pnas.90.11.4932]8506337
1991GIRARD, M, FLORES, M, BROM, S, ROMERO, D, PALACIOS, R, DAVILA, G. (1991). "Structural complexity of the symbiotic plasmid of Rhizobium leguminosarum bv. phaseoli". Journal Of Bacteriology. 173(8):2411-2419. [doi:10.1128/jb.173.8.2411-2419.1991]2013564
1991MARTINEZSALAZAR, J, ROMERO, D, GIRARD, M, DAVILA, G. (1991). "Molecular cloning and characterization of the recA gene of Rhizobium phaseoli and construction of recA mutants". Journal Of Bacteriology. 173(10):3035-3040. [doi:10.1128/jb.173.10.3035-3040.1991]2022610
1991ROMERO, D, BROM, S, MARTINEZSALAZAR, J, GIRARD, M, PALACIOS, R, DAVILA, G. (1991). "Amplification and deletion of a nod-nif region in the symbiotic plasmid of Rhizobium phaseoli". Journal Of Bacteriology. 173(8):2435-2441. [doi:10.1128/jb.173.8.2435-2441.1991]2013567
1991BROM, S, DELOSSANTOS, A, DELOURDESGIRARD, M, DAVILA, G, PALACIOS, R, ROMERO, D. (1991). "High-frequency rearrangements in Rhizobium leguminosarum bv. phaseoli plasmids". Journal Of Bacteriology. 173(3):1344-1346. [doi:10.1128/jb.173.3.1344-1346.1991]1991727
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1985Quinto, C, de la Vega, H, Flores López, M, Leemans, J, Cevallos Gaos, M, Pardo Galván, M, Azpiroz, R, Girard Cuesy, M, Calva Mercado, E, Palacios de la Lama, R. (1985). "NITROGENASE REDUCTASE - A FUNCTIONAL MULTIGENE FAMILY IN Rhizobium-phaseoli". PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 82(4):1170-1174. [doi:10.1073/pnas.82.4.1170]16593543