Energy Signaling in the Regulation of Gene Expression during Stress

By jpeza - Posted on 09 Noviembre 2010

Fecha Publicación: 
1 Ene 2010
Nombre de Revista: 
Datos del paper
Autor Principal: 
Elena Baena-Gonza´ lez1
Página Inicial: 
Página Final: 

Maintenance of homeostasis is pivotal to all forms of life. In the case of plants, homeostasis is constantly
threatened by the inability to escape environmental fluctuations, and therefore sensitive mechanisms must have evolved
to allow rapid perception of environmental cues and concomitant modification of growth and developmental patterns for
adaptation and survival. Re-establishment of homeostasis in response to environmental perturbations requires reprogramming
of metabolism and gene expression to shunt energy sources from growth-related biosynthetic processes to defense,
acclimation, and, ultimately, adaptation. Failure to mount an initial ‘emergency’ response may result in nutrient
deprivation and irreversible senescence and cell death. Early signaling events largely determine the capacity of plants
to orchestrate a successful adaptive response. Early events, on the other hand, are likely to be shared by different conditions
through the generation of similar signals and before more specific responses are elaborated. Recent studies lend
credence to this hypothesis, underpinning the importance of a shared energy signal in the transcriptional response to
various types of stress. Energy deficiency is associated with most environmental perturbations due to their direct or
indirect deleterious impact on photosynthesis and/or respiration. Several systems are known to have evolved for monitoring
the available resources and triggering metabolic, growth, and developmental decisions accordingly. In doing so,
energy-sensing systems regulate gene expression at multiple levels to allow flexibility in the diversity and the kinetics of
the stress response.

Dirección del Autor: 

Instituto Gulbenkian de Cieˆ ncia, Rua da Quinta Grande, 6, 2780-156 Oeiras, Portugal

Abiotic/environmental stress; metabolic regulation; cell signaling; gene expression; post-transcriptional control; transcription
[file] Molecular Plant 3(2)2010 300-313.pdf265.74 KB