A different genetic code in human mitochondria


By jpeza - Posted on 08 Noviembre 2010

Fecha Publicación: 
1 Ene 1979
Nombre de Revista: 
Datos del paper
Autor Principal: 
B. G. Barrell
Volumen: 
282
Issue: 
5735
Página Inicial: 
189
Página Final: 
194
Abstract: 

Comparison of the human mitochrondrial DNA sequence of the cytochrome
oxidase subunit II gene and the sequence of the corresponding beef heart
protein shows that UGA is used as a tryptophan codon and not as a
termination codon and suggests that AU A may be a methionine and not an
isoleucine codon. The cytochrome oxidase II gene is contiguous at its 5'
end with a tRNAAsp gene and there are only 25 bases at its 3' end before a tRNALys gene. These tRNAs are different from all other known tRNA sequences.

Dirección del Autor: 

MRC Laboratory of Molecular Biology, Hills Road, Cambridge, UK

Keywords: 
human mitochrondrial ; methionine ; cytochrome oxidase
PUBMED: 
226894
Coautores: 

Bankier AT, Drouin J.

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