Concomitant Use of an Oral Live Pentavalent Human- Bovine Reassortant Rotavirus Vaccine With Licensed


By jpeza - Posted on 07 Julio 2009

Fecha Publicación: 
1 Ene 2007
Datos del paper
Autor Principal: 
Zoe M. Rodriguez
MD
Volumen: 
26
Página Inicial: 
221
Página Final: 
226
Abstract: 

A live pentavalent rotavirus vaccine (PRV) containing

5 human-bovine (WC3) reassortants expressing human serotypes

G1, G2, G3, G4 and P1A8 was evaluated in a blinded,

placebo-controlled study. Possible interactions between PRV and

concomitantly administered licensed pediatric vaccines were investigated

in a United States-based nested substudy (Concomitant Use

Study) of the Rotavirus Efficacy and Safety Trial.

Dirección del Autor: 

*Clinical Research Center, University of Puerto Rico School of

Medicine, San Juan, PR; and †Merck & Co., Inc., West Point, PA.

Supported by Merck & Co., Inc

Keywords: 
rotavirus
pentavalent rotavirus vaccine
Coautores: 

Michelle G. Goveia, MD,† Jon E. Stek, MS,† Michael J. Dallas, PhD,†

John W. Boslego, MD,† Mark J. DiNubile, MD,† and Penny M. Heaton, MD†

AdjuntoTamaño
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