PART 3: ELEVATED LEVELS OF THE SALIVARY PROTEIN IMMUNOGLOBULIN E, NERVE GROWTH FACTOR....,


By jpeza - Posted on 26 Junio 2009

Fecha Publicación: 
1 Ene 2008
Nombre de Revista: 
Datos del paper
Autor Principal: 
BINIE VER LIPPS
Volumen: 
27
Issue: 
2
Página Inicial: 
109
Página Final: 
123
Abstract: 

It is known that serum frvrn allergy und usthmu patients contains ehated

h e l s of immunoglobuln E. This research reports ,use of a simple ELISA test for

measun'ng h e l s of endogenous proteins, including imrnunoglobulin E, nerue

growth factor; myoglobin, and insulin in non-invasively collected saliva. The

elevated immunoglobulin E is belimed to play a rok in mediatircg symptoms

of allergy/asthma, type 2 diabetes, and autoimmune diseases. Higtt lmels of

irrcmunoglobulin E were associated with increased glucose concerctration and

disruption of the regulation of lmels of other endogenous proteins. Saliua frvrn

norwcal people and patients sufm'ng from type 2 diabetes and variotts other

dismders, such as autoimmune diseases, were assayed for im,mttnoglobulin

E, neme gmwth factor, myoglobin, and insulin using a simple ELJSA test

employing the respective anti-sera. It was obserued that saliva specimens from

individuals with type 2 diabetes and van'ous autoimmune diseases contained

elevated h e l s of immunoglobulin E, neme growth factor; ncyoglobin, and

insulin i n compan'son with saliva samples from normal control individuals.

Dirección del Autor: 

Ophidia Products, Inc., Bellaire, Texas, USA

Keywords: 
protein markers
immunoglobulin E
nerve growth factor
AdjuntoTamaño
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