Genes of Human (Strain Wa) and Bovine (Strain UK) Rotaviruses That Code for Neutralization and Subgroup Antigens


By jpeza - Posted on 23 Marzo 2009

Fecha Publicación: 
19 Mar 1981
Nombre de Revista: 
Datos del paper
Volumen: 
112
Issue: 
1-2
Página Inicial: 
385
Página Final: 
390
Abstract: 

Sixteen rotaviral reassortants recovered from mixed infection with a (" rnlltant of bovine rotavirus (UK strain) and noucultivatable or cnltivatklbi" human rotavirlls (Wa strain) were gellotyped by polyacrylamide gel eleetr()phorp~k .'\ na1o'sjs of the )'i~assor· tants showe.d that the ninth Rl\ A g,'ne segment n)glllar1y segregated with th,' neutral· ization specificity turd the sinh RNA gene segment regularly segregated with the subgroup a.lltigenk sp(~c.ijkity detected hy immune adherence hemagglutination assay_ This indicates that the ninth RNA segment codes for the protein that induces and reacts with neutralizing antibodies while the sixth RN A segment codes for the su bgroup antigen. In addition, it appears that the fourth and/or fifth RNA segments may be respon"ibJe for restrictioIl of growth of the noncultivatabhl human rotavirlls in cell eulture.

Coautores: 

ANTHONY R. KALICA HARRY B. GREENBERG, .RICHARD G. WYATT, JORGE FLORES, MITZI M. SERENO, ALBERT Z. KAPIKIAN AND ROBERT M. CHANOCK

Clasificación del paper: 
bovine rotavirus;
AdjuntoTamaño
[file] Virology_1981_vol 112_ num1-2_pp 385-390.pdf3.35 MB