Functional Genomics of Eukaryotes Program

Publicaciones

#	Año	Ficha	Ligas
1	2013	Aparicio-Fabre, R., Guillén, G., Loredo, M., Arellano, J., Valdés-López, O., Ramirez, M., Iñiguez-Rabago, L.P., Panzeri, D., Castiglioni, B., Cremonesi, P., Strozzi, F., Stella, A., Girard, L., Sparvoli, F. and Hernández, G. (2013). *"Common Bean (Phaseolus vulgaris* L.) PvTIFY Orchestrates Global Changes In Transcript Profile Response To Jasmonate and Phosphorus Deficiency"*. Bmc Plant Biology*. 13:26	PUBMED: #23402340
2	2013	Ramirez, M., Guillén, G., Fuentes, S.I., Iñiguez-Rabago, L.P., Aparicio-Fabre, R., Zamorano-Sánchez, D., Encarnación, S., Panzeri, D., Castiglioni, B., Cremonesi, P., Sparvoli, F. and Hernández, G. (2013). "Transcript Profiling of Common Bean Nodules Subjected to Oxidative Stress". Physiol Plant.	PUBMED: #23432573
3	2013	Ramirez, M., Flores-Pacheco, G., Reyes, J.L., Álvarez, A.L., Drevon, J.J., Girard, L. and Hernández, G. (2013). "Two Common Bean Genotypes With Contrasting Response To Phosphorus Deficiency Show Variations In the microRNA 399-mediated PvPHO2 Regulation within the PvPHR1 Signaling Pathway". International Journal of Molecular Sciences. 14:1-x
4	2012	García-García, J.D., Olin-Sandoval, V., Saavedra, E., Girard, L., Hernández, G. and Moreno-Sánchez, R. (2012). *"Sulfate Uptake In Photosynthetic Euglena Gracilis. Mechanisms of Regulation and Contribution to Cysteine Homeostasis". Bba-gen Subjects. 1820*(10):1567-1575	PUBMED: #22609877
5	2012	Manoj-Kumar, A, Reddy, P.M., Manjulatha, M. and Blanco, L. (2012). "Polysaccharide-free Nucleic Acids and Proteins of Abelmoschus Esculentus for Versatile Molecular Studies". Mol Biol+. 46(4):535-541	PUBMED: #23113348
6	2012	Mendoza-Soto, A.B., Sánchez, F. and Hernández, G. (2012). "MicroRNAs As Regulators in Plant Metal Toxicity Response". Frontiers in Plant Science. 3:105	PUBMED: #22661980
7	2012	Silvente, S., Sobolev, A.P. and Lara-Flores, M. (2012). "Metabolite Adjustments in Drought Tolerant and Sensitive Soybean Genotypes in Response to Water Stress". Plos One. 7(6):e38554	PUBMED: #22685583
8	2011	Islas-Flores, T., Guillen, G., Alvarado-Affantranger, X., Lara-Flores, M., Sáchez, F. and Villanueva, M.A. (2011). *"PvRACK1 Loss-of-function Impairs Cell Expansion And Morphogenesis in Phaseolus vulgaris* L. Root Nodules"*. Mol Plant Microbe Interactions*. 24(7):819-826	PUBMED: #21425924
9	2011	Nava, E., Dávila-Martínez, Y., Arellano, J., Ortíz, A., Alvarez, L., Marquina, S. and Villarreal, M.L. (2011). *"Genetic Transformation of Solanum Chrysotrichum* By Agrobacterium tumefaciens and the Production of Antifungal Saponins"*. In vitro* Cell Dev-pl. 47(6):650-657
10	2010	Ortiz, A., Cardoso-Taketa, A., Monroy, M.R., Arellano, J., Hernández, G. and Villarreal, M.L. (2010). *"Transformed Cell Suspension Culture Of Galphimia Glauca* Producing Sedative NoR-friedelanes"*. Planta Med*. 76(4):386-392	PUBMED: #19809970
11	2010	Sreevidya, V.S., Hernández-Oane, R.J., Gyaneshwar, P., Lara-Flores, M., Ladha, J.K. and Reddy, P.M. (2010). "Changes in Auxin Distribution Patterns during Lateral Root Development in Rice". Plant Sci. 178(6):531-538
12	2010	Valdés-López, O., Yang, S.S., Aparicio-Fabre, R., Graham, P.H., Reyes, J.L., Vance, C.P. and Hernández, G. (2010). *"MicroRNA Expression Profile In Common Bean (Phaseolus vulgaris) Under Nutrient Deficiency Stresses and Manganese Toxicity". New Phytologist. 187*(3):1178-1183	PUBMED: #20553393
13	2010	Yang, S.S., Valdés-López, O., Xu, W.W., Bucciarelli, B., Gronwald, J.W., Hernández, G. and Vance, C.P. (2010). *"Transcript Profiling Of Common Bean (Phaseolus vulgaris* L.) Using the Genechip (r) Soybean Genome Array: Optimizing Analysis by Masking Biased Probes"*. Bmc Plant Biology*. 10	PUBMED: #20459672
14	2009	Arellano, J., Fuentes, S.I., Castillo-España, P. and Hernández, G. (2009). *"Regeneration of Different Cultivars of Common Bean (Phaseolus vulgaris* L.) via Indirect Organogenesis."*. Plant Cell Tiss Org*. 96(1):11-18
15	2009	Hernández, G., Valdés-López, O., Ramirez, M., Goffard, N., Weiller, G., Aparicio-Fabre, R., Fuentes, S.I., Erban, A., Kopka, J., Udvardi, M.K. and Vance, C.P. (2009). "Global Changes in the Transcript and Metabolic Profiles during Symbiotic Nitrogen Fixation in Phosphorus-stressed Common Bean Plants". Plant Physiol.	PUBMED: #19755543
16	2008	Blanco, L., Reddy, P.M., Silvente, S., Bucciarelli, B, Khandual, B, Alvarado-Affantranger, X, Sánchez, F., Miller, S, Vance, C and Lara-Flores, M. (2008). "Molecular Cloning, Characterization And Regulation of Two Different NADH-glutamate Synthase cDNAs in Bean Nodules". Plant Cell Environ. 31(4):454-472	PUBMED: #18182018
17	2008	Silvente, S., Reddy, P.M., Khandual, S., Blanco, L., Alvarado-Affantranger, X., Sánchez, F. and Lara-Flores, M. (2008). *"Evidence For Sugar Signalling in the Regulation of Asparagine Synthetase Gene Expressed in Phaseolus vulgaris* Roots and Nodules"*. J Exp Bot*. 59(6):1279-1294	PUBMED: #18407964
18	2008	Suárez, R., Wong-Villarreal, A., Ramirez, M., Barraza, A., Orozco, M.D., Cevallos, M.A., Lara-Flores, M., Hernández, G. and Iturriaga, G. (2008). *"Improvement Of Drought Tolerance and Grain Yield in Common Bean by Overexpressing Trehalose-6-phosphate Synthase in Rhizobia". Mol Plant Microbe Interactions*. 21(7):958-966	PUBMED: #18533836
19	2008	Valdés-López, O., Arenas-Huertero, C., Ramirez, M., Girard, L., Sánchez, F., Vance, C.P., Reyes, J.L. and Hernández, G. (2008). "Essential Role Of Myb Transcription Factor: PvPHR1 And microRNA: PvmiR399 in Phosphorus-deficiency Signalling in Common Bean Roots". Plant Cell Environ. 31(12):1834-1843	PUBMED: #18771575
20	2008	Valdés-López, O. and Hernández, G. (2008). "Transcriptional Regulation And Signaling in Phosphorus Starvation: What about Legumes?". J Integr Plant Biol. 50(10):1213-1222	PUBMED: #19017108
21	2007	Guo, X.W., Castillo-Ramírez, S., González, V., Bustos, P., Fernández, J.L., Santamaria, R.I., Arellano, J., Cevallos, M.A. and Dávila, G. (2007). *"Rapid Evolutionary Change of Common Bean (Phaseolus vulgaris* L) Plastome, and the Genomic Diversification of Legume Chloroplasts"*. BMC Genomics*. 8	PUBMED: #17623083
22	2007	Hernández, G., Ramirez, M., Valdés-López, O., Tesfaye, M., Graham, M.A., Czechowski, T., Schlereth, A., Wandrey, M., Erban, A., Cheung, F., Wu, H.C., Lara-Flores, M., Town, C.D., Kopka, J., Udvardi, M.K. and Vance, C.P. (2007). "Phosphorus Stress in Common Bean: Root Transcript and Metabolic Responses". Plant Physiol. 144(2):752-767	PUBMED: #17449651
23	2007	Shishkova, S., García-Mendoza, E., Castillo-Díaz, V., Moreno, N.E., Arellano, J. and Dubrovsky, J.G. (2007). "Regeneration of Roots from Callus Reveals Stability of the Developmental Program for Determinate Root Growth in Sonoran Desert Cactaceae". Plant Cell Rep. 26(5):547-557	PUBMED: #17136545
24	2006	Graham, M.A., Ramirez, M., Valdés-López, O., Lara-Flores, M., Tesfaye, M., Vance, C.P. and Hernández, G. (2006). *"Identification Of Candidate Phosphorus Stress Induced Genes In Phaseolus vulgaris* through Clustering Analysis across Several Plant Species"*. Funct Plant Biol*. 33(8):789-797
25	2006	Sreevidya, V.S., Rao, C.S., Sullia, S.B., Ladha, J.K. and Reddy, P.M. (2006). *"Metabolic Engineering Of Rice with Soybean Isoflavone Synthase for Promoting Nodulation Gene Expression in Rhizobia". J Exp Bot*. 57(9):1957-1969	PUBMED: #16690627
26	2005	Ramirez, M., Graham, M.A., Blanco, L., Silvente, S., Medrano-Soto, A., Blair, M.W., Hernández, G., Vance, C.P. and Lara-Flores, M. (2005). "Sequencing and Analysis of Common Bean ESTs. Building a Foundation for Functional Genomics". Plant Physiol. 137(4):1211-1227	PUBMED: #15824284
27	2005	Sreevidya, V.S., Hernandez-Oane, R.J., So, R.B., Sullia, S.B., Stacey, G., Ladha, J.K. and Reddy, P.M. (2005). *"Expression of the Legume Symbiotic Lectin Genes psl* and gs52 Promotes Rhizobial Colonization of Roots in Rice"*. Plant Sci. 169*(4):726-736
28	2003	Broughton, W.J., Hernández, G., Blair, M., Beebe, S., Gepts, P. and Vanderleyden, J. (2003). "Beans (phaseolus spp.) - Model Food Legumes". Plant Soil. 252(1):55-128
29	2003	Córdoba, E., Shishkova, S., Vance, C.P. and Hernández, G. (2003). *"Antisense Inhibition of NADH Glutamate Synthase Impairs Carbon/nitrogen Assimilation in Nodules of Alfalfa (Medicago sativa* L.)"*. Plant J*. 33(6):1037-1049	PUBMED: #12631328
30	2003	Guo, X.W., Flores, M., Mavingui, P., Fuentes, S.I., Hernández, G., Dávila, G. and Palacios, R. (2003). *"Natural Genomic Design In Sinorhizobium meliloti* Novel Genomic Architectures"*. Genome Res*. 13(8):1810-1817	PUBMED: #12902376
31	2003	Silvente, S., Camas, A. and Lara-Flores, M. (2003). *"Heterogeneity Of Sucrose Synthase Genes in Bean (Phaseolus vulgaris* L.): Evidence for a Nodule-enhanced Sucrose Synthase Gene"*. J Exp Bot*. 54(383):749-755	PUBMED: #12554718
32	2003	Silvente, S., Camas, A. and Lara-Flores, M. (2003). "Molecular Cloning of the cDNA Encoding Aspartate Aminotransferase from Bean Root Nodules and Determination of Its Role in Nodule Nitrogen Metabolism". J Exp Bot. 54(387):1545-1551	PUBMED: #12730270
33	2003	Suárez, R., Márquez, J., Shishkova, S. and Hernández, G. (2003). *"Overexpression of Alfalfa Cytosolic Glutamine Synthetase in Nodules and Flowers of Transgenic Lotus japonicus* Plants"*. Physiol Plant. 117*(3):326-336	PUBMED: #12654032
34	2003	Uhde-Stone, C., Zinn, K.E., Ramirez, M., Li, A.G., Vance, C.P. and Allan, D.L. (2003). "Nylon Filter Arrays Reveal Differential Gene Expression in Proteoid Roots of White Lupin in Response to Phosphorus Deficiency". Plant Physiol. 131(3):1064-1079	PUBMED: #12644659
35	2002	Camas, A., Cárdenas, L., Quinto, C. and Lara-Flores, M. (2002). *"Expression of Different Calmodulin Genes in Bean (Phaseolus vulgaris* L.): Role of Nod Factor on Calmodulin Gene Regulation"*. Mol Plant Microbe Interactions*. 15(5):428-436	PUBMED: #12036273
36	2002	Castillo, P., Zamilpa, A., Marquez, J., Hernández, G., Lara-Flores, M. and Alvarez, L. (2002). *"Comparative Study of Differentiation Levels and Valepotriate Content of in vitro* Cultures and Regenerated and Wild Plants of Valeriana edulis ssp. procera"*. J Nat Prod*. 65(4):573-575	PUBMED: #11975504
37	2002	Lira-Ruan, V., Ross, E.J.H., Sarath, G., Klucas, R.V. and Arredondo-Peter, R. (2002). *"Mapping And Analysis of a Hemoglobin Gene Family from Oryza sativa". Plant Physiol Biochem*. 40(3):199-202
38	2002	Mavingui, P., Flores, M., Guo, X.W., Dávila, G., Perret, X., Broughton, W.J. and Palacios, R. (2002). *"Dynamics Of Genome Architecture In Rhizobium* sp. Strain NGR234"*. J Bacteriol. 184*(1):171-176	PUBMED: #11741857
39	2002	Silvente, S., Blanco, L., Camas, A., Ortega, J.L., Ramirez, M. and Lara-Flores, M. (2002). *"Rhizobium etli* Mutant Modulates Carbon And Nitrogen Metabolism In Phaseolus vulgaris Nodules"*. Mol Plant Microbe Interactions*. 15(7):728-733	PUBMED: #12118889
40	2001	Aréchaga-Ocampo, E., Saenz-Rivera, J., Sarath, G., Klucas, R.V. and Arredondo-Peter, R. (2001). *"Cloning and Expression Analysis Of Hemoglobin Genes From Maize (Zea mays* ssp. mays) and Teosinte (Zea mays ssp. parviglumis)"*. Bba-gene Struct Express. 1522*(1):1-8	PUBMED: #11718894
41	2001	Fuentes, S.I., Allen, D.J., Ortiz-Lopez, A. and Hernández, G. (2001). "Over-expression of Cytosolic Glutamine Synthetase Increases Photosynthesis and Growth at Low Nitrogen Concentrations". J Exp Bot. 52(358):1071-1081	PUBMED: #11432923
42	2001	Lira-Ruan, V., Sarath, G., Klucas, R.V. and Arredondo-Peter, R. (2001). *"Synthesis Of Hemoglobins in Rice (Oryza sativa* Var. Jackson) Plants Growing in Normal and Stress Conditions"*. Plant Sci. 161*(2):279-287	PUBMED: #11448759
43	2001	Ross, E.J.H., Shearman, L., Mathiesen, M., Zhou, Y.J., Arredondo-Peter, R., Sarath, G. and Klucas, R.V. (2001). "Nonsymbiotic Hemoglobins in Rice are Synthesized during Germination and in Differentiating Cell Types". Protoplasma. 218(3-4):125-133	PUBMED: #11770429
44	2001	Shishkova, S., Arellano, J., Vance, C.P. and Hernández, G. (2001). "Transgenic Tobacco Plants That Overexpress Alfalfa NADH-glutamate Synthase have Higher Carbon and Nitrogen Content". J Exp Bot. 52(364):2079-2087	PUBMED: #11604446
45	2000	Arredondo-Peter, R., Ramírez, Y.M., Sarath, G. and Klucas, R.V. (2000). *"Sequence Analysis Of an Ancient Hemoglobin cDNA Isolated from the Moss Physcomitrella patens". Plant Physiol. 122*:1457
46	2000	Castillo, P., Marquez, J., Rubluo, A., Hernández, G. and Lara-Flores, M. (2000). *"Plant Regeneration From Callus and Suspension Cultures of Valeriana edulis* ssp. procera via Simultaneous Organogenesis and Somatic Embryogenesis"*. Plant Sci. 151*(2):115-119	PUBMED: #10808067
47	2000	Flores, M., Mavingui, P., Perret, X., Broughton, W.J., Romero, D., Hernández, G., Dávila, G. and Palacios, R. (2000). *"Prediction, Identification, And Artificial Selection Of DNA Rearrangements in Rhizobium: toward a Natural Genomic Design". P Nat Acad Sci USA*. 97(16):9138-9143	PUBMED: #10922070
48	2000	Hargrove, M.S., Brucker, E.A., Stec, B., Sarath, G., Arredondo-Peter, R., Klucas, R.V., Olson, J.S. and Phillips, G.N. (2000). "Crystal Structure of a Nonsymbiotic Plant Hemoglobin". Structure Fold Des. 8(9):1005-1014	PUBMED: #10986467
49	2000	Lira-Ruan, K., Sarath, G., Klucas, R.V. and Arredondo-Peter, R. (2000). *"Characterization Of Leghemoglobin from a Mimosoid Legume, Leucaena* Esculenta, Root Nodules"*. Brazilian Journal of Plant Physiology*. 12(1):37-44
50	2000	Luan, P., Aréchaga-Ocampo, E., Sarath, G., Arredondo-Peter, R. and Klucas, R.V. (2000). *"Analysis Of a Ferric Leghemoglobin Reductase from Cowpea (Vigna unguiculata) Root Nodules". Plant Sci. 154*(2):161-170	PUBMED: #10729615
51	2000	Schoenbeck, M.A., Temple, S.J., Trepp, G.B., Blumenthal, J.M., Samac, D.A., Gantt, J.S., Hernández, G. and Vance, C.P. (2000). *"Decreased Nadh Glutamate Synthase Activity in Nodules and Flowers of Alfalfa (Medicago sativa* L.) Transformed with an Antisense Glutamate Synthase Transgene"*. J Exp Bot*. 51(342):29-39	PUBMED: #10938793
52	1999	Castillo, M., Flores, M., Mavingui, P., Martínez-Romero, E., Palacios, R. and Hernández, G. (1999). *"Increase in Alfalfa Nodulation, Nitrogen Fixation, And Plant Growth by Specific DNA Amplification in Sinorhizobium meliloti". Appl Environ Microbiol*. 65(6):2716-2722	PUBMED: #10347066
53	1999	Mandon, K., Michel-Reydellet, N., Encarnación, S., Kaminski, P.A., Leija, A., Cevallos, M.A., Elmerich, C. and Mora, J. (1999). *"Poly-beta-hydroxybutyrate Turnover In Azorhizobium caulinodans* is Required for Growth and Affects nifA Expression"*. J Bacteriol. 180*(19):5070-5076	PUBMED: #9748438
54	1999	Ramirez, M., Valderrama, B., Arredondo-Peter, R., Soberón, M., Mora, J. and Hernández, G. (1999). *"Rhizobium etli* Genetically Engineered For The Heterologous Expression of Vitreoscilla sp. Hemoglobin: Effects on Free-living and Symbiosis"*. Mol Plant Microbe Interactions*. 12(11):1008-1015
55	1998	Arredondo-Peter, R., Hargrove, M.S., Moran, J.F., Sarath, G. and Klucas, R.V. (1998). "Plant Hemoglobins". Plant Physiol. 118(4):1121-1125	PUBMED: #9847086
56	1998	Flores, M., Mavingui, P., Girard, L., Perret, X., Broughton, W.J., Martínez-Romero, E., Dávila, G. and Palacios, R. (1998). *"Three Replicons Of Rhizobium* Sp. Strain NGR234 Harbor Symbiotic Gene Sequences"*. J Bacteriol. 180*(22):6052-6053	PUBMED: #9811668
57	1998	Mavingui, P., Laeremans, T., Flores, M., Romero, D., Martínez-Romero, E. and Palacios, R. (1998). *"Genes Essential For Nod Factor Production And Nodulation Are Located on a Symbiotic Amplicon (AMPRtrCFN299pc60) in Rhizobium* tropici"*. J Bacteriol. 180*(11):2866-2874	PUBMED: #9603874
58	1998	Mendoza, A., Valderrama, B., Leija, A. and Mora, J. (1998). *"Nifa-dependent Expression Of Glutamate Dehydrogenase in Rhizobium etli* Modifies Nitrogen Partitioning during Symbiosis"*. Mol Plant Microbe Interactions*. 11(2):83-90	PUBMED: #9450332
59	1997	Mavingui, P., Flores, M., Romero, D., Martínez-Romero, E. and Palacios, R. (1997). *"Generation Of Rhizobium* Strains with Improved Symbiotic Properties by Random DNA Amplification (RDA)"*. Nat Biotechnol*. 15(6):564-569	PUBMED: #9181580
60	1996	Arellano, J., Vázquez, F., Villegas, T. and Hernández, G. (1996). *"Establishment of Transformed Root Cultures of Perezia cuernavacana* Producing the Sesquiterpene Quinone Perezone"*. Plant Cell Rep*. 15(7):455-458
61	1996	Cevallos, M.A., Encarnación, S., Leija, A., Mora, Y. and Mora, J. (1996). *"Genetic And Physiological Characterization of a Rhizobium etli* Mutant Strain Unable to Synthesize Poly-beta-hydroxybutyrate"*. J Bacteriol. 178*(6):1646-1654	PUBMED: #8626293
62	1995	Hernández, G., Ramirez, M., Suárez, R. and Fuentes, S.I. (1995). *"Root Exuded Nod-gene Inducing Signals Limit The Nodulation Capacity of Different Alfalfa Varieties with Rhizobium* meliloti"*. Plant Cell Rep*. 14(10):626-629
63	1995	Mendoza, A., Leija, A., Martínez-Romero, E., Hernández, G. and Mora, J. (1995). *"The Enhancement of Ammonium Assimilation in Rhizobium etli* Prevents Nodulation of Phaseolus vulgaris"*. Mol Plant Microbe Interactions*. 8(4):584-592	PUBMED: #8589413
64	1993	Fuentes, S.I., Suárez, R., Villegas, T., Castro Acero, L. and Hernández, G. (1993). *"Embryogenic Response Of Mexican Alfalfa (Medicago-sativa) Varieties". Plant Cell Tiss Org*. 34(3):299-302
65	1991	Padilla, J.E., Miranda-Ríos, J. and Sánchez, F. (1991). "Nodulin Regulation in Common Bean Nodules Induced by Bacterial Mutants". Mol Plant Microbe Interactions. 4(5):433-439
66	1990	Soberón, M., Membrillo-Hernández, J., Aguilar, G.R. and Sánchez, F. (1990). *"Isolation of Rhizobium* phaseoli Tn5-induced Mutants With Altered Expression of Cytochrome Terminal Oxidase o and Oxidase aa3"*. J Bacteriol. 172*(3):1676-1680	PUBMED: #2155209
67	1989	Folch, J., Antaramián, A., Rodríguez, L., Bravo, A., Brunner, A. and González, A. (1989). *"Isolation And Characterization Of a saccharomyces* cerevisiae Mutant with Impaired Glutamate Synthase Activity"*. J Bacteriol. 171*(12):6776-6781	PUBMED: #2687252
68	1989	Soberón, M., Olamendi, J., Rodríguez, L. and González, A. (1989). *"Role Of Glutamine Aminotransferase In Glutamine Catabolism by saccharomyces* cerevisiae under Microaerophilic Conditions"*. J. Gen. Microbiol.. 135*:2693-2697	PUBMED: #2698914
69	1989	Soberón, M., William, H.D., Poole, R.K. and Escamilla, E. (1989). *"Isolation Of A Rhizobium* phaseoli Cytochrome Mutant with Enhanced Respiration and Symbiotic Nitrogen Fixation"*. J Bacteriol. 171*(1):465-472	PUBMED: #2644201
70	1988	Bravo, A. and Mora, J. (1988). *"Ammonium Assimilation In Rhizobium* phaseoli By the Glutamine Synthetase-glutamate Synthase Pathway"*. J Bacteriol. 170*(2):980-984	PUBMED: #2892829
71	1988	Bravo, A., Becerril, B. and Mora, J. (1988). *"Introduction Of The Escherichia coli* Gdha Gene into Rhizobium phaseoli: Effect on Nitrogen Fixation"*. J Bacteriol. 170*(2):985-988	PUBMED: #2892830
72	1988	Flores, M., González, V., Pardo, M.A., Leija, A., Martínez-Romero, E., Romero, D., Piñero, D., Dávila, G. and Palacios, R. (1988). *"Genomic Instability In Rhizobium* phaseoli"*. J Bacteriol. 170*(3):1191-1196	PUBMED: #3343217
73	1987	Campos, F., Padilla, J.E., Vázquez, M., Ortega, J.L., Enríquez, C. and Sánchez, F. (1987). *"Expression Of Nodule-Specific Genes In Phaseolus vulgaris* L."*. Plant Mol Biol*. 9(6):521-532
74	1987	González, A., Rodríguez, L., Folch, J., Soberón, M. and Olivera, H. (1987). *"Coordinated Regulation Of Ammonium Assimilation And Carbon Catabolism by Glyoxylate in saccharomyces* cerevisiae"*. J. Gen. Microbiol.. 133*:2497-2501	PUBMED: #2896226
75	1987	Lomnitz, A., Calderón, J., Hernández, G. and Mora, J. (1987). "Functional-analysis of Ammonium Assimilation Enzymes in Neurospora-crassa". J. Gen. Microbiol.. 133:2333-2340
76	1987	Martínez-Romero, E., Palacios, R. and Sánchez, F. (1987). *"Nitrogen Fixing Nodules Induced By Agrobacterium tumefaciens* Harboring Rhizobium phaseoli Plasmids"*. J Bacteriol. 169*(6):2828-2834	PUBMED: #3584072
77	1987	Mora, Y., Hernández, G. and Mora, J. (1987). *"Regulation Of Carbon and Nitrogen Flow by Glutamate Synthase in Neurospora crassa". J. Gen. Microbiol.. 133*(7):1667-1674	PUBMED: #2959749
78	1987	Padilla, J.E., Campos, F., Conde, V., Lara-Flores, M. and Sánchez, F. (1987). *"Nodule-Specific Glutamine Synthetase Is Expressed before The Onset Of Nitrogen Fixation in Phaseolus vulgaris* L."*. Plant Mol Biol*. 9(1):65-74
79	1987	Sánchez, F., Campos, F., Padilla, J.E., Bonneville, J.M., Enríquez, C. and Caput, D. (1987). *"Purification, Cdna Cloning, And Developmental Expression of the Nodule-Specific Uricase from Phaseolus vulgaris* L."*. Plant Physiol*. 84(4):1143-1147	PUBMED: #16665575
80	1987	Servín-González, L., Ortíz, M., González, A. and Bastarrachea, F. (1987). *"Glna Mutations Conferring Resistance to Methylammonium in Escherichia coli* K12"*. J. Gen. Microbiol.. 133*(6):1631-1639	PUBMED: #2889793
81	1987	Soberón, M. and González, A. (1987). *"Glutamine Degradation through The Omega-amidase Pathway In saccharomyces* cerevisiae"*. J. Gen. Microbiol.. 133*(1):9-14	PUBMED: #3309146
82	1987	Soberón, M. and González, A. (1987). *"Physiological Role Of Glutaminase Activity In saccharomyces* cerevisiae"*. J. Gen. Microbiol.. 133*(1):1-8	PUBMED: #3309138
83	1986	Hernández, G. and Mora, J. (1986). *"Glutamine Synthesis Regulates Sucrose Catabolism In Neurospora crassa". J. Gen. Microbiol.. 132*:3315-3323
84	1986	Hernández, G., Mora, Y. and Mora, J. (1986). *"Regulation Of Glutamine Synthesis by Glycine and Serine in Neurospora crassa". J Bacteriol. 165*(1):133-138	PUBMED: #2867084
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Programa de Genómica Funcional de Eucariotes

Responsable del Programa: Georgina Hernández D, Ph.D.

Este programa de investigación estudia a las PLANTAS, cómo representativas de los sistemas eucariotes.

Desde 2013 este programa se encuentra en proceso de restructuración, buscando incorporar nuevos científicos / proyectos.

La investigación actual se enfoca en las plantas leguminosas. Las leguminosas pueden establecer simbiosis con bacterias de la familia rhizobiaceae para capturar el nitrógeno atmosférico directamente y así mantener el crecimiento vegetal. Las leguminosas juegan un papel importante en la agricultura sustentable: en el manejo efectivo de fertilizantes, en el mejoramiento de la calidad del suelo y en proteger a los mantos acuíferos de la contaminación.

La principal línea de investigación del grupo G Hernández / M Ramírez es: “La genómica funcional del frijol”. El frijol (Phaeolus vulgaris L.) es la leguminosa más importante para el consumo humano en el mundo; su producción en México es elevada y es la principal fuente proteica en la dieta humana. Establece simbiosis con las bacterias fijadoras de N: Rhizobium etli y R. tropici. La producción de frijol es baja, en parte, por las plagas e insectos pero también por limitantes que incluyen las deficiencias nutricionales, la acidez del suelo y la toxicidad por metales. La secuencia genómica de P. vulgaris se liberó recientemente (www.phytozome.net). La investigación post-genómica del grupo usa la plataforma de genómica funcional, desarrollada por ellos mismos, para investigar las respuestas / regulación de la fijación simbiótica de N en condiciones de estrés abiótico. La plataforma de investigación incluye: la transcriptómica (micro-arreglos, RNA-seq), el perfil de expresión de los reguladores globales: factores de transcripción y micro- RNAs, la genética reversa (silenciamiento por RNAi, sobre-expresión) para el análisis de funciones génicas en plantas compuestas de frijol.

Alternative splicing in common bean

The post-genomic era lead to the discovery of alternative splicing in eukaryotes (plants and animals). Splicing of introns from a pre-mRNAs transcribed from a single eukaryotic gene can be regulated by different factors and so generate alternative spliced transcripts or isoforms. The analysis of the great complexity at the transcriptional level generated by alternative splicing in legumes has only begun. Based in our common bean transcriptome data we are analyzing the alternative splicing in this legume (collaboration with S. Jackson, U. Georgia).

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MicroRNAs as global regulators of common bean symbiosis and of the response to abiotic stress

Micro-RNAs (miRNAs), a class of small non-coding RNAs 21-24 nt long, are essential post-transcriptional regulators for plant development and response to stress; their characterization and function in legumes is yet scant. We are interested in enhancing the knowledge about miRNAs in common bean, focusing in SNF nodules. Projects in this area include: a) miRNAs expression profiles through RNA-seq and b) defining specific functions of selected miRNAs in nodule development and/or in the response of SNF common bean plants to abiotic stress using reverse genetic approaches.

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Symbiotic transcriptome (common bean / rhizobium) of the response to abiotic stress

The effectiveness of the atmospheric N-fixation process occurring in the legume-rhizobia symbiosis (symbiotic nitrogen fixation = SNF) is highly dependent on the adequate gene expression both in the macro- and micro-symbiont. One of our research interests is to perform combined transcriptome analyses of the Rhizobium etli bacteroids and the common bean nodule cells to generate integral knowledge of global gene expression and regulation in this symbiosis. Such project is done in collaboration with the group of L.

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Common bean expression atlas: transcription factors

Our group has participated in pioneer research on common bean transcriptome. This work has been done in collaboration with Carroll P. Vance, U. Minnesota – USDA, and other colleagues.